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CLAV AVICEL & SYLOID

Name: CLAV AVICEL & SYLOID
Brand: IPSUM LIFESCIENCES LLP
Price: 1800 INR
Availability: InStock

Price 1800 INR/ Kilograms

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MOQ : 25 Kilograms

CLAV AVICEL & SYLOID Specification

Boiling point
Not applicable (decomposes)

Melting Point
Decomposes before melting

Loss on Drying
< 5.0%

Moisture (%)
< 5.0%

HS Code
3824

Place of Origin
India

Particle Size
D90 < 50 m

Heavy Metal (%)
< 0.001%

Molecular Weight
Varies depending on blend ratio

EINECS No
None assigned

Molecular Formula
C8H9NO5 (Clavulanate), Others depend on constituents

Ph Level
5.0 - 7.5

Residue on Ignition
< 0.5%

Acid Value
< 1.0 mg KOH/g

Assay
> 98%

Storage
Store in cool, dry place below 25C, protect from moisture

Other Names
Clavulanate Avicel Blend, Clavulanic Acid Mixture

CAS No
58001-44-8

Type
Pharmaceutical Excipient Blend

Grade
Pharmaceutical Grade

Usage
Used in the formulation of pharmaceuticals, particularly for stabilizing active compounds and improving drug delivery

Purity
> 98%

Appearance
Fine Powder

Application
Pharmaceutical Tablet & Capsule Formulation

Raw Material
Avicel (Microcrystalline Cellulose), Syloid (Silicon Dioxide), Clavulanic Acid or its salts

Smell
Odorless

Color
White to Off-White

Form
Powder

Identification
Conforms to specification by IR and chemical test

Microbial Limits
Total aerobic microbial count < 1000 cfu/g, Yeast & Mold < 100 cfu/g, E. coli & Salmonella absent

Country of Export
India

Stability
Stable under recommended storage conditions

Packaging
HDPE drums, 25 kg net or customized as per requirement

Intended Use
For use as an inactive ingredient in solid oral pharmaceutical formulations only

Solubility
Dispersible in aqueous media

Shelf Life
24 Months from date of manufacture in original sealed packaging

Bulk Density
0.3 - 0.5 g/cm³

About CLAV AVICEL & SYLOID

Clavulanate (Clavulanic Acid):

Clavulanate is a I2-lactamase inhibitor used in combination with certain antibiotics to enhance their effectiveness against I2-lactamase-producing bacteria. It is typically a white to off-white crystalline powder crucial for combating bacterial resistance mechanisms.

Avicel (Microcrystalline Cellulose):

Avicel is a widely used pharmaceutical excipient derived from cellulose. It appears as a white, free-flowing powder with excellent compressibility and binding properties. Avicel is essential in tablet formulations for improving tablet hardness and ensuring uniform drug release.

Syloid (Silica Gel):

Syloid refers to synthetic amorphous silica, commonly used in pharmaceuticals as a desiccant or as a flow aid in powdered formulations. It presents as a white, amorphous powder with particle sizes tailored to optimize powder flow and stability in pharmaceutical products.

Pharmaceutical-Grade Excellence

CLAV AVICEL & SYLOID is meticulously crafted as an excipient blend tailored for tablet and capsule formulations. With a purity of over 98% and verified by both IR and chemical tests, it meets pharmaceutical industry standards. Its composition ensures compatibility and safety for solid oral medications, reinforcing stability and performance.

Superior Quality and Safety Standards

This excipient blend adheres to strict microbial and heavy metal limits to guarantee product safety. Each batch undergoes comprehensive quality checks, including loss on drying and residue on ignition tests, ensuring consistent performance. The product's fine particle size and moisture control facilitate easy formulation and enhanced shelf life.

Versatile Application and Packaging

CLAV AVICEL & SYLOID offers versatile use in various pharmaceutical dosage forms by stabilizing active compounds and improving drug delivery. It is packed in robust 25 kg HDPE drums or custom packages as needed, providing flexibility for manufacturers and maintaining integrity during storage and transport.

FAQ's of CLAV AVICEL & SYLOID:

Q: How should CLAV AVICEL & SYLOID be stored to ensure maximum shelf life?

A: This product should be stored in a cool, dry place below 25C, away from moisture, and kept in its original sealed HDPE packaging to maintain its stability and integrity over the 24-month shelf life.

Q: What is the primary use of CLAV AVICEL & SYLOID in pharmaceutical manufacturing?

A: It functions as an inactive excipient blend, incorporated mainly into tablet and capsule formulations to stabilize active pharmaceutical ingredients and improve drug delivery efficiency.

Q: When is it advisable to use CLAV AVICEL & SYLOID in drug formulation processes?

A: CLAV AVICEL & SYLOID is recommended during the development of solid oral dose medications where enhancement of active compound stability and control over release profiles are desired.

Q: Where is CLAV AVICEL & SYLOID manufactured and exported from?

A: The blend is manufactured and supplied from India, adhering to pharmaceutical grade standards, and is available for international export under HS Code 3824.

Q: What quality standards does CLAV AVICEL & SYLOID conform to?

A: It complies with identification and purity standards (>98%), demonstrates low microbial and heavy metal content, and passes strict IR and chemical identification tests, ensuring suitability for pharmaceutical use.

Q: How does the product's bulk density and particle size contribute to its application in tablets and capsules?

A: A bulk density of 0.3 - 0.5 g/cm3 and a fine particle size (D90 < 50 m) allow for uniform blending and compaction, facilitating efficient processing during tablet and capsule manufacturing.

Q: What benefits does using CLAV AVICEL & SYLOID provide to pharmaceutical manufacturers?

A: Utilizing this blend enhances product stability, optimizes active ingredient delivery, and supports efficient manufacturing due to its dispersibility, safety, and tailored physicochemical properties.

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